Healthcare AI Benchmark

Isaac OneHealth Ultra, the clinical AI platform purpose-built for dentistry, has achieved a perfect 100% score on the most challenging 324 questions from the United States Medical Licensing Examination (USMLE)—the gold standard benchmark used to assess expert-level medical reasoning.

This makes Isaac only the second healthcare AI in history to reach this milestone and the first dental-trained AI to demonstrate such cross-domain clinical intelligence, validating that dental AI can meet and exceed world-class healthcare standards.

Supported by thousands of practicing dentists and built with a hybrid training philosophy that blends evidence-based literature, real-world clinical insights, and continuous specialist feedback, Isaac delivers actionable clinical reasoning that rivals the best in healthcare.

Below you can download the USMLE PDFs—including Isaac's benchmark performance—showcasing this groundbreaking achievement and what it means for the future of AI in clinical practice.